When a post office opened in 1891, the name was standardised as a single word; the Tophouse locality is located near State Highway 63.
It is 117 km long and runs between the settlements of Renwick (in Marlborough) and Kawatiri Junction (in the Tasman region) via Saint Arnaud, providing a bypass of the city of Nelson.
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At Kawatiri Junction, it terminates at SH 6 between Murchison and the Hope Saddle.
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SH 63 begins just to the east of Renwick at SH 6, and parallels the course of the Wairau River for 93 kilometres, originally to the south of the river before crossing to the north side about 20 km from the Marlborough/Tasman border, while passing through the settlements of Wairau Valley, Hillersden and Tophouse.
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