One of the few preserved historic original buildings, it was the residence of the notable Knoblauch family with members like the architect Eduard Knoblauch or the physicist Karl-Hermann Knoblauch.
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The Rococo façade at the intersection of Mühlendamm and Poststraße became famous as Berlin's "finest corner", until the house was demolished in 1936 for the laying out of the enlarged Mühlendamm street.
There is a Zille Memorial statue created in 1964–65 by Heinrich Drake in the Lapidary within Köllnischer Park and a 2007 statue by Thorsten Stegmann in the Nikolaiviertel, both also in Mitte.