Simon Belmont and Mega Man were appropriately replaced by Samus Aran, the Metroid heroine who had not appeared in the cartoon, and Mother Brain's second-in-command became Uranos, the demigod from Kid Icarus.
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The comics are based upon Nintendo video game and television intellectual property from Super Mario Bros., Game Boy, The Legend of Zelda, Captain N: The Game Master, Metroid, and Punch-Out!!.
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