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He was physician to Burhan Nizam Shah I of the Nizam Shahi dynasty of Ahmadnagar, and concurrently to several successive Portuguese Viceroys and governors of Goa: one of these granted him a lease of the island of Bombay, though he never lived there.
But soon, Shahaji with the assistance of Bijapur, placed an infant scion of the Nizam Shahi dynasty, Murtaza on the throne and he became the regent.