X-Nico

2 unusual facts about O-linked glycosylation


O-linked glycosylation

O-linked glycosylation occurs at a later stage during protein processing, probably in the Golgi apparatus.

Both of these fucosyltransferases have been localized to the endoplasmic reticulum, which is unusual for glycosyltransferases, most of which function in the Golgi apparatus.



see also

GALNT1

GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins.