He arrived in Kenya in 1901 for big game hunting, playing host to former US President Theodore Roosevelt, during his famous 1911 safari at their ranch, Juja Farm (later a popular location for film crews).
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It was in this house that Macmillan housed his friend and former American President Theodore Roosevelt, as he wrote his biography.
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The other prominent person who had stayed in the house was the wartime British Prime Minister Sir Winston Churchill.