Old Louisville is one of the most liberal neighborhoods in Louisville, as evidenced by the General Election results in 2004, where it voted for John Kerry by a 60% margin and against a proposal to amend the state constitution to define marriage as "between one man and one woman" by a 66% margin (the proposal passed 75% to 25% in Kentucky).
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The area of 6th and Hill Streets in the neighborhood was the setting of the best selling novel Mrs. Wiggs of the Cabbage Patch by Louisvillian Alice Hegan Rice.
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