At first she disliked her youthful bridegroom, but when he returned wounded from an expedition to Algiers in 1541 her aversion was turned to affection.
In 1566 he was knighted by the second Duke of Parma, Ottavio Farnese, and made ambassador to Flanders.
House of Farnese | Alessandro Farnese | Ottavio Rinuccini | Alexander Farnese, Duke of Parma | Villa Farnese | Pier Luigi Farnese | Ottavio Farnese | Francesco Farnese, Duke of Parma | Farnese Hercules | Alexander Farnese | Alessandro Farnese (cardinal) | Ottavio Vannini | Ottavio Piccolomini | Ottavio Farnese, Duke of Parma | Ottavio Cinquanta | Ottavio Barbieri | Ottavio | Giulia Farnese | Francesco Farnese | Farnese Gardens | Farnese gardens | Farnese Bull | Alexander Farnese, Prince of Parma |
Pier Luigi and his son, Ottavio, declared they would have pay 9,000 golden ducati every year to the Holy See, and, in exchange, they gave back the Duchies of Camerino and Nepi.