Pediococcus acidilactici have been used to treat dogs with digestive disorders and also those dogs which were infected by Parvovirus.
Prior to treatment with orally administered mixtures of Pediococcus acidilactici and Saccharomyces boulardii the dogs diagnosed with parvovirus infection were shown to exhibit severe gastro-intestinal distress such as vomiting and bloody diarrhea.