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The society sponsored Paul Chomedey de Maisonneuve and Jeanne Mance, a lay woman, to go to Ville Marie with French colonists to evangelize the Native Americans, and establish a hospital, which became the Hôtel-Dieu de Montréal, to care for the poor, founded by Mance in 1642.
It is written that the Governor of Montreal Paul Chomedey de Maisonneuve offered "a land adjacent to the property of the brewery" to the newly wed.