Its major roads include east-to-west Highway 22, William Penn Highway, and Freemansburg Road and north-to-south Highway 33, Route 191, Butztown Road/Hecktown Road, Farmersville Road, and Main Street Extension.
Its primary north-to-south routes are the two-lane Nazareth Pike (Route 191) and the Route 33 Expressway.
Interstate 78 crosses Lower Saucon east-to-west with access from 412 at the Bethlehem/Hellertown line and Highway 33 in the northeast.
North-to-south Highway 33 crosses the NW portion of Palmer and interchanges with 22, Hecktown Road, and 248 just beyond its western boundary.
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