Peripheral neuropathy and CNS effects are associated with the use of isoniazid and are due to pyridoxine (vitamin B6) depletion, but are uncommon at doses of 5 mg/kg.
Serial Peripheral Interface Bus | Peripheral neuropathy | Peripheral | neuropathy | Radial neuropathy | Peripheral myelin protein 22 | peripheral chemoreceptors | peripheral | Kjer's optic neuropathy | Diabetic neuropathy |
Named after Scottish anatomist Charles Bell, who first described it, Bell's palsy is the most common acute mononeuropathy (disease involving only one nerve) and is the most common cause of acute facial nerve paralysis (>80%).
He then carried out studies between 1922 and 1924 at universities of Munich and Hamburg in Germany as well as at University of Vienna, Austria, specializing in neuropathy.
Alternatively, a European Medicines Agency approved drug Tafamidis or Vyndaqel now exists which stabilizes transthyretin tetramers comprising wild type and different mutant subunits against amyloidogenesis halting the progression of peripheral neuropathy and autonomic nervous system dysfunction.