Sharpe was elected as an Adams-Clay Democratic-Republican to the 18th United States Congress, holding office from March 4, 1823 to March 3, 1825.
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He was an unsuccessful candidate for re-election to the 19th United States Congress in 1824.
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He successfully contested the election of Peter Sharpe to the 17th United States Congress and served from December 12, 1821, to March 3, 1823.