Pekowi, a band of the Shawnee Native American tribe and the origin of the word "Piqua"
Buster Keaton (1895–1966), acclaimed actor and film director.
The Piqua Coca-Cola Bottling Company, owned by the Lange family, was located on the downtown square at the northeast corner of Main and High streets.
The transmitter site of WHIO-FM (formerly WPTW-FM,WCLR and WDPT respectively and licensed to Piqua) is located south of the community on Aiken Road adjacent to State Route 66.
WHIO-FM, a radio station (95.7 FM) licensed to Piqua, Ohio, United States, known as WDPT-FM from 2000 to 2006.
The road was formed along the route cut through the area by George Rogers Clark in 1782 during his campaigns against the natives at Lower Piqua and Upper Piqua.
From 2000 until 2006, "The Point" aired classic hits from the late 1970s and 1980s and was briefly simulcast on WDTP, 95.3 in Xenia before reverting to the WZLR calls as classic rock-formatted "The Eagle." Before that it was WCLR at first as "Clear 95" airing easy listening music (as did its predecessor WPTW-FM for many years) when the transmitter was moved from its studios to its present location near the rural community of Houston just north of Piqua in 1986.
Ultimate Oldies Radio was also heard on its first translator W268AX at 101.5 MHz from Old Troy Pike (SR 202) in north Dayton with a power of 106 watts which provided a wider coverage area reaching downtown Dayton, Moraine, Troy, and the fringe areas in Piqua to the north and Miamisburg to the south.