The pistol has also made the transition to the NFL, mainly being used by the Carolina Panthers with Cam Newton and Robert Griffin III of the Washington Redskins, as well as the aforementioned Kaepnernick with the San Francisco 49ers, who in the NFL Playoffs versus the Green Bay Packers set the all-time single game rushing record for a quarterback with 181 yards.
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The Wolf Pack also became the first team in college football history with three 1,000-yard rushers in the same season: quarterback Colin Kaepernick and running backs Luke Lippincott and Vai Taua.
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The San Francisco 49ers began employing the pistol offense with the emergence of former Nevada quarterback Colin Kaepernick.