Sterilised bulb scales, leaf bases or flower stalks can be used in tissue culture.
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His father was the eminent botanist, Gottlieb Haberlandt, plant tissue culture theorist and visionary; his grandfather was the European 'soybean' pioneer and trailblazer Friedrich J. Haberlandt.
In 1962, Skoog and Toshio Murashige published what is probably the best-known paper in plant tissue culture; in a fruitless attempt to discover a yet-unknown plant growth regulator in tobacco juice for his doctoral thesis, Murashige and Skoog instead developed a greatly improved salt base for the sterile culture of tobacco.
He is most widely known for his efforts in creating the plant tissue culture medium known as Murashige and Skoog medium.