Night monkeys constitute one of the few monkey species that are affected by the often deadly human malaria protozoan Plasmodium falciparum, making them useful as non-human primate experimental models in malaria research.
These changes are thought to give rise to the scientifically and clinically interesting phenomenon that those with SAO exhibit: a marked in vivo resistance to infection by the causative pathogen of malaria, Plasmodium falciparum.
Plasmodium | Plasmodium falciparum | Plasmodium species infecting mammals other than primates | Plasmodium lepidoptiformis |
From 1989 to 1999, eleven volunteers recruited from the United States Public Health Service, United States Army, and United States Navy were immunized against Plasmodium falciparum by the bites of 1001 to 2927 mosquitos that had been irradiated with 15,000 rads of gamma rays from a Co-60 or Cs-137 source.