The show was created by Albert Espinosa and draws on his childhood experiences as a hospital patient.
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In October 2011, it was announced that Steven Spielberg's DreamWorks and Marta Kauffman had reached an agreement with TV3 for an American remake of Polseres Vermelles.
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In November 2013, The Fox Network announced it will be adapting the series with Margaret Nagle from Boardwalk Empire set to write the script.