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The town has become a big center for plastics, with the manufacture of Lexan taking place just south of town at the SABIC plant; in addition, Port of Indiana-Mount Vernon, is an important part of the city's industry.
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Port of Indiana-Mount Vernon, a major publicly funded riverport, is located just east of Mt. Vernon.
The Northwestern University Lakefill is an area of land that was reclaimed from Lake Michigan in 1964-1969 from landfill materials made available by the construction of the Port of Indiana.