Kramarsky's family put the painting up for auction at Christie's New York on May 15, 1990, where it became famous for Ryoei Saito, honorary chairman of Daishowa Paper Manufacturing Co., paying US$82.5 million for it, making it then the world's most expensive painting.
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Van Gogh also wrote to Wilhelmina regarding the Portraits of Madame Ginoux he painted first in Arles in 1888 and again in February 1890 while at the hospital in Saint-Rémy.
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The doctor's "sensitive face", which Van Gogh famously wrote to Paul Gauguin carried "the heartbroken expression of our time", is described by Robert Wallace as the portrait's focus.
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