An early enforcement action of the United States Pure Food and Drug Act in 1909 concerned a shipment of Mapleine confiscated in Chicago.
The first glass-lined tanks were built by the Dickson Manufacturing Company in 1887; and the Pure Food and Drug Act of 1906 increased use of the these tanks for milk products.
The Swamp Root formulation fell out of favor after the advent of the 1906 Pure Food and Drug Act, which resulted in the federal government imposing testing and labeling requirements on a variety of products, including patent medicines with dubious claims.
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He was the lead House sponsor of the Kefauver Harris Amendment, an amendatory act to the federal Pure Food and Drug Act, the law that mandates that pharmaceutical companies disclose the side effects of medications approved by the United States Food and Drug Administration for sale in the United States.
In 1912, even though Coca-Cola had won the case, two bills were introduced to the U.S. House of Representatives to amend the Pure Food and Drug Act, adding caffeine to the list of "habit-forming" and "deleterious" substances, which must be listed on a product's label.
These three issues—an imitation under the same name, false or misleading ingredient listing, and misleading labelling—were all a part of the Pure Food and Drug Act section defining "misbranded".