In Chongqing, he worked directly under Zhou Enlai, who recognized his interest in foreign affairs and took him as his personal assistant for international matters.
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With the outbreak of the Cultural Revolution in 1966, Qiao Guanhua was first identified as member of the counter-revolutionary clique ruling the Foreign Ministry along with Chen Yi and Ji Pengfei.
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Qiao Guanhua engaged mainly in journalism with the pen name of Qiaomu (喬木, meaning Tree, also the pen name of Hu Qiaomu), working on the international review of several newspapers in Hong Kong.