Albert, Count of Nassau-Dillenburg (1 November 1596 in Dillenburg – 16 June 1626 in Quakenbrück) was a son of Count George of Nassau-Dillenburg and his first wife, Anna Amalia of Nassau-Saarbruucken.
Dietrich Hermann Hegewisch (15 December 1746 – 4 April 1812) was a German historian who was a native of Quakenbrück.
The Grand Duchy of Oldenburg gained an important link to the south in 1876 with the so-called Southern Railway from Oldenburg via Quakenbrück as far as Eversburg on the Osnabrück–Rheine line.
Heinrich Friedrich Wilhelm Beythien (13 February 1873 in Quakenbrück – 17 März 1952 in Berlin-Wilmersdorf) was a German politician and functionary of the DVP and Nazi Party (NSDAP).
From 1810 to 1813 Löningen belonged to the Arrondissement Quakenbrück.
In 1879, the Rhenish Railway Company (Rheinische Eisenbahn-Gesellschaft, RhE) opened its own North Sea route from Duisburg via Rheine to Quakenbrück and so made the station one of the major railway junctions in north-western Germany.