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Following the major reorganization of the Allied air forces in the North African and Mediterranean Theater of Operations (MTO) at the Casablanca Conference in January 1943, Air H.Q. East Africa became a sub-command of the RAF Middle East Command, itself a sub-command of the Mediterranean Air Command.
Throughout this important period of World War II during which air interdiction was practiced and developed, Tedder was always at the forefront as Air Commander-in-Chief of RAF Middle East Command, Mediterranean Air Command (MAC), Mediterranean Allied Air Forces, and as General Dwight D. Eisenhower's Deputy Supreme Allied Commander for planning the air operations for D-Day Normandy.