X-Nico

2 unusual facts about Raffaele Piria


Aromatic sulfonation

A classic named reaction is the Piria reaction (R. Piria, 1851) in which nitrobenzene is reacted with a metal bisulfite forming an aminosulfonic acid as a result of combined nitro group reduction and sulfonation.

Salix alba

The active extract of the bark, called salicin, after the Latin name Salix, was isolated to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist, who then succeeded in separating out the acid in its pure state.



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