X-Nico

unusual facts about Renin-angiotensin system



Effective arterial blood volume

The kidney mechanisms used to restore EABV include, (1) sympathetic nerve activity; (2) Atriopeptin (ANP) secretion from the atria; (3) Starling forces; (4) Renin-angiotensin-aldosterone system.

Epimer

Epimerisation can be spontaneous (generally a slow process), or catalyzed by enzymes, e.g. the epimerization between the sugars N-acetylglucosamine and N-acetylmannosamine, which is catalyzed by Renin-Binding Protein.

Nesiritide

Nesiritide works to facilitate cardiovascular fluid homeostasis through counterregulation of the renin-angiotensin-aldoesterone system, stimulating cyclic guanosine monophosphate, leading to smooth muscle cell relaxation.

Robert Tigerstedt

Tigerstedt's work on renin was probably inspired by Brown-Sequard's work examining the effect of organ extracts on physiological function.


see also