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John de Vere, 12th Earl of Oxford (23 April 1408 – 26 February 1462), was the son of Richard de Vere, 11th Earl of Oxford (1385?–15 February 1417), and his second wife, Alice Sergeaux (1386–1452).
In May 1416 Oxford was invested with the Order of the Garter, and in that year sailed with the fleet to relieve Harfleur, taking part in the naval battle at the mouth of the Seine on 15 August.