However, as she grew older, and medical techniques slowly improved, she was diagnosed with what was then called Rickets, or what is more modernly called Osteogenesis Imperfecta.
Dent's disease was first described by Charles Enrique Dent and M. Friedman in 1964, when they reported two unrelated British boys with rickets associated with renal tubular damage characterized by hypercalciuria, hyperphosphaturia, proteinuria, and aminoaciduria.
He was one of the seven physicians who aided Francis Glisson in the observations preparatory to the publication of the Tractatus de Rachitide (on rickets) in 1650.