After an unsuccessful last-ditch effort to lure Red Grange to Rochester (he instead signed with the Chicago Bears), the team suspended operations after the 1925 NFL season; by this point, the team had been losing money (to the point where Lyons' house had been foreclosed upon because of his dumping of virtually all his assets into the team) and had been a traveling team for two seasons (1920 and 1925).
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The Buffalo Bisons also had a year out from the league, and the Rochester Jeffersons, after missing two seasons of play, finally folded.