Roosevelt and his son Kermit undertook the adventure after the former U.S. president's failed attempt to regain the office as the "Bull Moose" candidate in 1912.
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In 1927 American explorer George Miller Dyott led a second trip down the river, independently confirming Roosevelt's discoveries.
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It was Father Zahm who talked President Roosevelt into participating in what came to be known as the Roosevelt-Rondon Scientific Expedition to South America, and which would also include Theodore's son, Kermit, and Colonel Da Silva Candido Rondon, to go up the Rio da Dúvida (River of Doubt, now the Roosevelt River).