Among theater companies which he helped organize were Harlem's American Negro Theatre in 1940, which started the careers of Harry Belafonte, Ruby Dee, Sidney Poitier, among others.
Ruby Dee, Adilah Barnes, Kim Staunton, Michele Shay and Linda Gravatt appeared in a 1998 production of her first play, The Bridge Party, at the University of Michigan, a work inspired by local events.
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She also describes her personal and professional relationships with Ruby Dee, Ossie Davis, Beah Richards, and Frank Silvera.
The network featured a variety of different programming, including a popular soap opera The Story of Ruby Valentine, which was based on CBS's We Love and Learn and As the Twig is Bent, and starred Juanita Hall, Ruby Dee and Terry Carter.
His other film credits include The Jackie Robinson Story (1950), Carmen Jones (1954), Porgy and Bess (1959), A Raisin in the Sun (1961), with Sidney Poitier, Ruby Dee and Claudia McNeil, and a memorable turn as Mr. Prentice (again playing opposite Poitier) in the 1967 feature film Guess Who's Coming to Dinner.
Sankofa's supporters, including Coretta Scott King, bishop Desmond Tutu, Al Sharpton, Jesse Jackson, and celebrities Danny Glover, Kenny Rogers, Lionel Richie, Harry Belafonte and Ruby Dee, brought his case international attention, arguing that his conviction was based on the claim that the testimony of a single eyewitness who said she saw him for a few seconds in the dark parking lot committing the murder.
William Worthy, along with actors Ossie Davis and Ruby Dee, writers James Baldwin, Julian Mayfield and John Killens, poets Maya Angelou, Sonia Sanchez and Leroi Jones, historian John Henrik Clarke, and photojournalist Gordon Parks was one of the most important political allies of Malcolm X.