Signal Transducer and Activator of Transcription 5 refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins.
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STAT5 can also form homo-tetramers, usually in concert with the histone methyltransferase EZH2, and act as a trancriptional repressor.
STAT5 |
There are seven mammalian STAT family members that have been identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6.