In the year 1900, aged twenty, Uyenishi travelled to London at the invitation of Edward William Barton-Wright, the founder of the eclectic martial art of Bartitsu.
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Soon after his arrival in London, Uyenishi joined fellow expatriate Japanese wrestler Yukio Tani on the teaching faculty of Barton-Wright's Bartitsu Club in Shaftesbury Avenue.
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After the Bartitsu Club closed down (circa 1902), Uyenishi continued his work as a professional wrestler and also taught jiujitsu classes at the self defence academy that had been established by his former Bartitsu Club colleague, Pierre Vigny.
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Notable individuals who were directly influenced by Sadakazu Uyenishi's teaching included William Garrud, whose book "the Complete Jujitsuan" (published in 1914) became a standard reference work on the subject; Edith Garrud, who went on to establish jujitsu classes for members of the militant Suffragist movement; and Mrs. Emily Watts, whose 1906 book The Fine Art of Jujitsu was the first English work to record Kodokan judo kata.