The diocese consists of fifteen towns in the province of Catania: Caltagirone, Castel di Judica, Grammichele, Mazzarrone, San Michele di Ganzaria, Raddusa, Ramacca, Mirabella Imbaccari, Scordia, Militello in Val di Catania, Palagonia, Mineo, Licodia Eubea, San Cono and Vizzini.
San Michele di Ganzaria borders the following municipalities: Caltagirone, Mazzarino, Piazza Armerina, San Cono.
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