In early 1919, Rustemi began further studies at the Arberesh College of Saint Adrian in San Demetrio Corone in Calabria.
After completing his studies at the Collegio di Sant'Adriano (the college of Saint Adrian) in the Arbëreshë town of San Demetrio Corone, Calabria, he returned to Durrës where he joined the patriotic circles of the city.
Muço initially studied in San Demetrio Corone, Calabria and later graduated from the faculty of law of the University of Bologna.
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After completing his secondary education in the Italo–Albanian college of San Demetrio Corone (Collegio of Sant'Adriano), in the Italian province of Cosenza, Spiro Koleka continued his higher education at the University of Pisa (1930–1934) where he graduated as a Civil Engineer.