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Concerned about the floods ravaging the Guangdong Province, Lee left for Cornell University in the United States to undertake a special study on River Conservancy and Sanitary engineering in 1919.
As a member of the American Public Health Association, he was chairman of its laboratory section and supervised several editions of its Standard Methods of Water Analysis. Qualified through his consulting work, he became a member of the sanitary engineering division of American Society of Civil Engineers, served on its executive committee for five years and was its chairman for two years.