Biologists believe that this isolation has contributed to evolution of subspecies such as the San Diego mountain kingsnake.
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A few of these species are Johnston's rockcress, Casey's June beetle, Coachella Valley round-tailed ground squirrel, Munz's mariposa lily, San Jacinto bush snapdragon, Santa Rosa Mountain linanthus, Tahquitz ivesia, and Ziegler’s aster.
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The National Monument legislation (introduced on February 16, 2000, by Congresswoman Mary Bono) authorized the establishment of a management plan that included cooperative agreements with existing organizations, such as that of the Cahuilla peoples and the University of California, as well as maintaining most of the historical land uses, except mining and geothermal activities.
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