As part of its modern artistic development, many upcoming Spanish painters and sculptors are developing their work in Santaella, with the sculptor Francisco Luque as the best known representative.
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Felipe II grants its jurisdictional independence, to pass, later, to be erected in marquisate, recovering its independence in 1735.
Marie Marguerite of Bourbon, Duchess of Anjou (née María Margarita Vargas Santaella; born 21 October 1983, Caracas) is a Venezuelan heiress and wife of Louis Alphonse of Bourbon, Duke of Anjou, who is considered by Legitimists to be the head of the French Royal House making Marie Marguerite the Legitimist titular queen consort of France.