With time, they were all annexed by the chieftainship of Cuzcatlán, today the modern city of Antiguo Cuscatlan a city and municipality, part of the San Salvador Metropolitan Area (AMSS).
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On the ashes of the once mighty Cuzcatlan in 1525, Pedro de Alvarado's cousin Diego de Alvarado established the Villa De San Salvador.
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On June 6, 1524, Pedro de Alvarado crossed the Paz river with a few hundred soldiers and subdued the Cacique of Izalco (the first major city state en route to Cuzcatlan).
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Others such as Chalchuapa and Cihuatán became allies with the Pipils, but also eventually became Pipil city states.
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Some city states such as Tehuacán allowed them free entrance avoiding destruction and eventually with time they became Pipil cities themselves.