In 1840, he ran for Mayor of Buffalo, New York, but was defeated by the Whig candidate Sheldon Thompson in a close race: 1135 for Thompson, 1125 for Barker.
In early 1810, he moved to Lewiston, New York where he entered into the shipbuilding business and mercantile trade along the Great Lakes with Senior Partner, Jacob Townsend and Alvin Bronson.
Hunter S. Thompson | Richard Thompson | Richard Thompson (musician) | Fred Thompson | Tommy Thompson | Danny Thompson | Thompson | Thompson submachine gun | Thompson River | Sheldon Silver | James R. Thompson | William Hale Thompson | Emma Thompson | Thompson Twins | Thompson Square | Dorothy Thompson | Sheldon Cooper | Jenny Thompson | Gina Thompson | Francis Thompson | Ernest Thompson Seton | Thompson Country | Ronny Thompson | Daley Thompson | Vicki Lewis Thompson | Sir Henry Thompson, 1st Baronet | Sheldon Leonard | Sheldon | Porl Thompson | Nucky Thompson |