X-Nico

3 unusual facts about Sin Nombre virus


Sin Nombre

Sin Nombre virus, the prototypical etiologic agent of hantavirus cardiopulmonary syndrome (HCPS)

Sin Nombre virus

Interestingly, when the prototype sequence (NMH15) of SNV detected in tissues from an HPS case was compared with the sequence of the SNV isolate (NMR11; isolated in Vero E6 cells from Peromyscus maniculatus trapped in the residence of the same case), only 16 nucleotide changes were found, and none of these changes resulted in alterations in amino acid sequences of viral proteins.

These include El Moro Canyon virus associated with the western harvest mouse, Reithrodontomys megalotis, Tula virus with Microtus arvalis and M. rossiaemeridionalis, Rio Segundo virus with the Mexican harvest mouse, R. mexicanus, Isla Vista virus with the California vole, M. californicus, and Prospect Hill-like viruses in Microtus species.


Rockport virus

Phylogentic analysis shows Rockport virus clusters geographically with Andes virus (ANDV) and Sin Nombre virus (SNV), both of which are carried by sigmodontine and Neotominae rodents.


see also