In 1947, he moved to the United States and from 1947 to 1953 served as Rosh Yeshiva at the Hebrew Theological College in Skokie, Illinois.
He later worked as a volunteer coach for mentally-handicapped children in Skokie, Illinois.
In 2007, thirty-two of his watercolors were put on display at the Sevan Gallery in Skokie, Illinois.
In this case, Skokie, Illinois wanted abandoned quarries filled with water, but not connected to another or navigable body of water to serve as a site for a solid waste facility.
Neier was criticized for his decision to have the ACLU support the National Socialist Party of America, a Neo-Nazi group, in its efforts to march in Skokie, Illinois in the case National Socialist Party of America v. Village of Skokie, despite the presence in Skokie of large numbers of Jews and Holocaust survivors.
The road parallels U.S. Route 41 (Skokie Highway), which is only a few miles to the west, and Illinois Route 137 (Amstutz Expressway), which is only a few miles to the east.
They gave lectures in Washington, D.C., (at Georgetown University and Library of Congress), New York (at Columbia University), Chicago (at Harold Washington College), Skokie (for the Holocaust Memorial Foundation of Illinois), Palo Alto, in the San Francisco Bay area (Stanford University) and Los Angeles (at the Los Angeles Museum of the Holocaust).
"Skokie was a great issue," he said in 1980.
USR was founded in 1976 in Chicago, Illinois (and later moved to Skokie, Illinois), by a group of entrepreneurs, including Casey Cowell, who served as CEO for most of the company's history and Paul Collard who designed modems into the mid-1980s.