The Great Central built a new line from Marylebone to join this railway at South Ruislip (then called Northolt Junction).
The GWR/GCR Joint line to High Wycombe carried services from both Paddington and Marylebone.
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The two former GWR main lines from London Paddington: the Great Western Main Line (GWML) of 1838-1841 to Bristol Temple Meads railway station (passing through Slough, Reading and Swindon), and the 1903 New North Main Line (NNML) via Greenford to Northolt Junction, which is the start of the Great Western and Great Central Joint Railway line, split at Old Oak junction.