In 1837 he was active in organizing residents in the Southern Tier to lobby the New York and Lake Erie Railroad to create the Cohocton Route, which aided in the economic development of New York's central and southwestern counties.
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During the professional years on New York's southern tier (1875–1882), d'Autremont campaigned actively for Horace Greeley in 1872, Samuel Tilden in 1876, and Winfield Scott Hancock in 1880.
It is found from Baffin Island west along the Hudson Bay and arctic coasts of the Nunavut and Northwest Territories mainland and the southern tier of Arctic Islands to northern Yukon, Alaska, and Eurasia.
Route 895 crosses it after crossing the southern tier of Schuylkill County and ends at an interchange with Route 248 across the river in Bowmanstown.
An example was when the New York Times reported in mid-June 2012 that Governor Andrew Cuomo and his staff were deliberating on a plan to restrict hydrofracking to five counties in the 'southern tier' of New York, along the Pennsylvania border, where the Marcellus shale is deepest and drilling is least likely to pollute well water supplies in those aquifers.