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William Lee Popham (1885-1953) was an American author, evangelist, Chautauqua speaker, and real estate developer who was important in the growth of Apalachicola, Florida and St. George Island, FL.
A boat was purchased to ferry investors to St. George Island, and Popham Oyster Factory No. 1 was constructed in Apalachicola at the mouth of the Apalachicola River.