Cassano Spinola borders the following municipalities: Carezzano, Gavazzana, Novi Ligure, Pozzolo Formigaro, Sant'Agata Fossili, Sardigliano, Serravalle Scrivia, Stazzano, and Villalvernia.
Cesare Zerba was born in Castelnuovo Scrivia, and studied at the seminaries in Stazzano and Tortona, the Pontifical Roman Athenaeum S. Apollinare in Rome, and the University of Pavia.