A doctor of medicine at Montpellier, Champier was the personal physician of Antoine, Duke of Lorraine, whom he followed to Italy with Louis XII, attending to several battles, and finally settling in Lyon.
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Symphorien Champier (1471–1538), a Lyonnese doctor born in Saint-Symphorien, France, was a relation of the Chevalier de Bayard through his wife, Marguerite Terrail.
A letter by Robert, as Bishop of Ross, in recommendation of Symphorien Champier, a doctor of medicine at Lyon and the personal physician of Antoine, Duke of Lorraine, was published in the compendium Que in hoc opusculo habentur: Duellum Epistolare, et, Item Complures Illustrium Virorum Epistolae ad Symphorianum Camperium, Venice/Lyons (1519).