In 2009, a group of researchers from the Seoul National University (Republic of Korea) demonstrated that the copper-peptide GHK-Cu stimulated proliferation of keratinocytes and increased expression of integrins and p63 protein in the epidermal stem cells.
The p63 factor is involved in inhibiting EMT and reduction of certain p63 isoforms may be important in the development of epithelial cancers.
Limb–mammary syndrome is a cutaneous condition characterized by p63 mutations.
TP63 |