Unlike ziconotide, TROX-1 is not so selective, and also blocks the intrathecally, by injection into the spinal fluid.
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It was developed as a potential analgesic after the discovery that the selective ziconotide is an active analgesic with similar efficacy to strong opioid drugs but comparatively milder side effects.
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TROX-1 is a drug which acts as a potent blocker of the Cav2 type calcium channels.
The Germany based TROX GmbH has been founded in 1951 in Neukirchen-Vluyn, a small town nearby Düsseldorf and is a globally active manufacturer of air distribution and air conditioning components.