The roughly 14 kilometre long river has its source in a small, wooded area on the municipal boundary between Muchow and Stolpe at a height of about 42 metres above sea level.
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From here the Tarnitz flows initially for about a kilometre in a southwestern and then southern direction, running east of the villages of Muchow and Zierzow.
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In the parish of Prislich meadows and larger woods frame its river banks, otherwise it runs almost entirely through arable fields from which many ditches drain into the Tarnitz.